Psychiatric Drug Database: Dosing, Risks, Binding

What it covers

The Drug Database is the core table of PsychoPharmRef. It lists antidepressants, antipsychotics, mood stabilizers, sleep medications, anxiolytics, stimulants, non-stimulant ADHD drugs, VMAT2 inhibitors for movement disorders, and medications for substance use, one row per drug. You can search by name, narrow the table to one category, or filter by pharmacologic class (for example SSRI, SNRI, TCA, MAOI, first- and second-generation antipsychotics, Z-drugs, benzodiazepines, orexin antagonists) and by route of administration from the sidebar.

Columns in the table

Group	Columns
Identity	Drug and brand name, class, active enantiomer, route
Pharmacokinetics	Parent half-life, active metabolites, protein binding
Special populations	Renal adjustment, hepatic adjustment, geriatric notes, pregnancy, breastfeeding
Safety signals	QT prolongation, lipid and glucose risk, EPS risk
Pharmacodynamics	Pre- and post-synaptic binding and a receptor chart

Select any drug name to open its detail view, which adds its mechanism, pharmacokinetics, P450 interactions, FDA-approved indications, and dosing considerations.

Sorting by side-effect risk

The side-effect sort reorders the table by relative risk for one adverse effect, from least to most risky or the reverse, and can break ties with a second effect. The effects available are sedation, weight gain, anticholinergic effects, orthostatic hypotension and dizziness, sexual dysfunction, EPS and akathisia, metabolic effects, insomnia and activation, hyperprolactinemia, nausea and GI upset, cognitive impairment, and cardiac or QT effects. When a sort is active, risk columns appear next to the drug name.

Limitations

The table summarizes prescribing information and the pharmacology literature for quick comparison. It does not replace current FDA labeling, an interaction checker, or patient-specific dosing decisions, and relative risk ratings are comparisons between drugs rather than incidence figures.