PsychoPharmRef Clinical Tools
Interactive clinical decision support tools for psychiatry. Free, evidence-based, designed for point-of-care use.
Psychopharmacology
Chem Structure: Compare Psychotropic Molecules
Compare two psychotropic drugs side by side: 2D and 3D structures, molecular weight, cLogP, polar surface area, …
CYP450 Interactions for Psychiatric Medications
See which psychiatric drugs are substrates, inhibitors or inducers of CYP1A2, 2B6, 2C9, 2C19, 2D6 and 3A4, with strong, …
FDA Indication Search: Approved Drugs by Diagnosis
Type a psychiatric diagnosis to list the medications with an FDA-approved indication for it, grouped by indication, with …
Find Complementary Psychiatric Medications
Pick a reference drug to see curated augmentation strategies and ranked agents that share an indication but act through …
Find Similar Medications: Switching After Poop-Out
Rank psychiatric drugs by pharmacologic similarity to one that stopped working, using receptor binding, action, class, …
PK Curve Comparison: Psychiatric Drug Half-Lives
Overlay estimated plasma concentration curves for up to 8 psychiatric drugs to compare Tmax and half-life, using a …
Psychiatric Drug Database: Dosing, Risks, Binding
Searchable table of psychiatric medications with half-life, renal and hepatic adjustment, QT, metabolic and EPS risk, …
Psychiatric Medication Comparison: 2 to 6 Drugs
Compare 2 to 6 psychiatric drugs side by side: receptor binding, P450 interactions, QT flags, predicted side-effect …
Psychiatric Medication Price Comparison
Compare cash prices for psychiatric drugs at Mark Cuban Cost Plus Drugs and HealthWarehouse, with CMS NADAC wholesale …
Psychotropic Tolerability Comparison: Side Effects
Compare weight, sedation, sexual, anticholinergic and QTc burden for two to four antidepressants or antipsychotics, with …
Receptor Binding Profiles: Psychiatric Drug Ki Values
Look up receptor Ki values for psychiatric drugs, compare two drugs side by side, and view pKi by drug class as bar …
Receptor Glossary: Clinical Effects of Receptor Binding
Look up what blocking or activating SERT, D2, 5-HT2A, H1, M1, alpha-1 and other receptors does clinically, with drug …
Clinical Tools
24-Hour Alcohol Intake Calculator: Standard Drinks
Convert a patient's 24-hour drinks to US standard drinks and grams of ethanol, with editable volume and ABV and a …
24-Hour Caffeine Intake Calculator (mg per day)
Add up a patient's caffeine from coffee, tea, soda, energy drinks, and tablets over 24 hours, with editable mg per …
24-Hour THC Intake Calculator: Total mg THC
Estimate total THC in milligrams from the cannabis products a patient used in 24 hours, from flower and vapes to …
Aid to Capacity Evaluation (ACE): Capacity Note
Work through the Aid to Capacity Evaluation for one medical decision: seven domains rated yes, unsure, or no, an overall …
Anticholinergic Burden Calculator: ACB and ARS
Build a medication list and total its anticholinergic burden on the ACB and ARS scales, with flags for strong agents and …
ASD Severity Levels: DSM-5 Support Needs Rating
Rate DSM-5 autism severity levels 1–3 for social communication and restricted, repetitive behaviors, with specifiers and …
DSM-5-TR Substance Use Disorder Criteria Tool
Check the 11 DSM-5-TR substance use disorder criteria for a chosen substance, get mild, moderate, or severe, add …
DV / IPV Assessment: HITS Screen and Danger Review
Score the 4-item HITS intimate partner violence screen (4-20, positive at 11 or more) and record a structured lethality …
Fatigue and Low Energy Workup: Labs and Differential
Check red flags and symptoms in a patient with low energy to build a suggested lab panel and differential across organ …
Medication Taper and Cross-Taper Schedule Planner
Build a dated taper, titration, or two-drug cross-taper schedule for a psychiatric drug, with step sizes in percent or …
Movement Disorder Assessment: Bedside Exam Note
Describe each abnormal movement on seven axes, region by region, match it to a phenomenology category, and copy a …
OTC Sleep Aid Comparison: Evidence, Dose and Risks
Compare 19 non-prescription sleep aids, including antihistamines, melatonin, herbals, magnesium and cannabinoids, by …
Psychiatric Medication History Form and Trial Review
Record a patient's prior psychiatric medication trials, side effects and reasons for stopping, then generate an …
QTc Calculator and Tisdale QT Risk Score
Calculate QTc with Bazett and Fridericia, score Tisdale QT prolongation risk, and review QT-prolonging psychiatric and …
Refill Calendar: Fill Dates, Usage and Med Sync
Count days between fills, check over- or underuse against the prescribed rate, project refill dates forward or back, and …
SMI-FRAIL-20: Medicaid Medical Frailty Documentation
A 20-item checklist (0–60) for documenting medical frailty in severe mental illness for the Medicaid work-requirement …
Rating Scales
ADL / IADL Checklist: Functional Independence
Rate 9 basic and 8 instrumental activities of daily living as independent, needs help, dependent or cannot do, and copy …
AIMS Tardive Dyskinesia Scale: Exam and TD Screen
Score the Abnormal Involuntary Movement Scale with body-area subtotals, the Schooler–Kane tardive dyskinesia screen, and …
ASRS v1.1 Adult ADHD Screener: Part A and Part B
Score the 18-item Adult ADHD Self-Report Scale v1.1: Part A is positive with 4 or more of 6 items in the shaded range, …
Autism Spectrum Quotient (AQ-10 and AQ-50) Scorer
Score the AQ-10 short screener or the full 50-item AQ-50 for adult autistic traits, with five domain subscores and a …
BAT Burnout Assessment Tool: Scores and Cut-offs
Score the Burnout Assessment Tool (BAT-23 work or BAT-22 general) as 1–5 domain means, compare with the 2023 validated …
BFCRS Catatonia Rating Scale: Screen and Severity
Score the Bush-Francis Catatonia Rating Scale: the 14-item screen (positive at 2 or more signs) and the 23-item severity …
BPRS Brief Psychiatric Rating Scale Calculator
Rate the 18-item clinician-scored BPRS with anchor definitions, five subscale totals and Leucht 2005 severity anchors, …
CIDI 3.0 Bipolar Screen: Symptom Count and Risk
Work through the CIDI 3.0 bipolar screen: two stem questions, a Criterion B gate, and nine symptoms mapped to a risk …
CIWA-Ar Alcohol Withdrawal Scale: Score Calculator
Score the 10-item clinician-rated CIWA-Ar (0–67) for acute alcohol withdrawal severity, with item anchors, vital signs …
Clinical Dementia Rating (CDR): Global and Sum of Boxes
Rate the six CDR domains, derive the global CDR with the Morris (1993) rules, and get the CDR Sum of Boxes stage with a …
COWS Calculator: Opioid Withdrawal Severity
Score the 11-item Clinical Opiate Withdrawal Scale (COWS, 0–48), see the withdrawal severity band and buprenorphine …
Epworth Sleepiness Scale (ESS): Score and Severity
Score the 8-item Epworth Sleepiness Scale (0-24), see the current Johns severity band, and copy a dated plain-text …
GAD-7 Anxiety Scale: Score and Severity Bands
Score the 7-item GAD-7 anxiety scale from 0 to 21, see the minimal, mild, moderate or severe band, and copy a dated …
Insomnia Severity Index (ISI): Score and Bands
Score the 7-item Insomnia Severity Index (0–28) across four severity bands, with item anchors, CBT-I guidance and a …
MSI-BPD: Borderline Personality Disorder Screen
Score the 10-item McLean Screening Instrument for BPD. A total of 7 or more is a positive screen. Copy a dated …
PANSS Calculator: PANSS-6 and Full PANSS-30
Score the PANSS-6 or full 30-item PANSS with subscales, Marder factors and Leucht CGI-linked severity bands, then copy a …
PCL-5 PTSD Checklist: Score, Clusters and Cut-off
Score the 20-item PCL-5 (0–80) with DSM-5 cluster subscores, a provisional diagnosis check, the probable-PTSD cut-off …
PHQ-9 Depression Screener: Score and Severity Bands
Score the 9-item PHQ-9 (0–27) for depression screening and severity, with an Item 9 safety alert and a plain-text report …
SLUMS Exam: Cognitive Screening with Domain Scores
Score the 30-point SLUMS cognitive screen with education-adjusted cut-offs, a 1-minute fluency timer, seven domain …
Suicide Risk Assessment: C-SSRS Screen and Full Scale
C-SSRS screen with risk triage, the full C-SSRS for ideation, intensity, behavior and lethality, and an AFSP risk and …
Y-BOCS OCD Severity Scale: Score and Severity Bands
Score the 10-item Yale-Brown Obsessive Compulsive Scale (0–40) with obsession and compulsion subtotals, a symptom …
YMRS Calculator: Young Mania Rating Scale
Score the 11-item Young Mania Rating Scale (YMRS, 0–60) with anchor text for every rating, see the remission threshold …
Neuroscience
3D Brain Explorer: Neuroanatomy for Psychopharmacology
Rotate a 3D brain atlas and click structures such as the DLPFC, amygdala, striatum, raphe, and locus coeruleus to see …
Brain Regions in Neuropsychiatric Disorders
Reference cards linking 15 psychiatric and neurological disorders, from PTSD and depression to schizophrenia and …
Cellular Neuroscience for Psychiatry: Cell Atlas
Eighteen nerve and glial cell types that matter in psychiatry: anatomy, physiology, receptors, disease, and how pH, …
Cognitive Domains Reference: MoCA and SLUMS Mapping
Reference to seven cognitive domains, the MoCA and SLUMS items that test each one, the disorders that impair them, and …
Therapy Courses
ABA and Naturalistic Approaches for Autism: Module 2
Therapy-course module on assent-based ABA for autism: discrete trial training, PRT and ESDM, FBA and functional …
Behavioral Activation & CBT for Depression Course
A how-to module for delivering behavioral activation and CBT for depression, with activity monitoring, values, …
CBT for Anger and Parent Management Training
Course module on CBT for anger in adults and teens and Parent Management Training for caregivers, with anger logs, PMT …
CBT for Insomnia (CBT-I) Course: How-To Module
Learn to deliver CBT-I with a sleep diary that computes sleep efficiency, a sleep-restriction calculator with weekly …
CBT for Psychosis (CBTp): Therapy Course Module 6
A how-to module on CBT for psychosis: collaborative formulation, working with voices and beliefs, functioning goals, and …
EMDR Therapy for PTSD: Therapy Course Module 8
A how-to module on the eight-phase EMDR protocol: target sequencing, resourcing, NC/PC with SUDS and VOC, and set-by-set …
Exposure Therapy and ERP for OCD: Course Module
Course module on exposure-based CBT for anxiety and ERP for OCD using the inhibitory-learning model, with fear …
Foundations of Behavioral and CBT Therapy Course
Module 1 of the therapy course: behavioral and cognitive principles, functional analysis, case formulation, session …
Integration and Implementation: Therapy Module 7
The capstone therapy-course module: transdiagnostic sequencing, combining therapy with medication, fidelity and …
Marriage and Couples Therapy: Course Module
Course module on couples therapy: safety screening and secrets policy, the main evidence-based models, couple protocols …