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Nicotine Dependence

Most people who smoke or vape want to quit, and most who succeed took more than one try. Quitting is a skill you build — and the right tools stack the odds in your favor.

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Why It's Hard

Nicotine is genuinely addictive — it rewires the brain's reward system, so cravings and irritability on quitting are physical, not a lack of willpower.

This applies to cigarettes and to vaping, which can deliver even more nicotine.

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Medications Double Your Odds

  • Nicotine replacement — patch for a steady base, plus gum or lozenge for cravings.
  • Varenicline (Chantix) — often the most effective option.
  • Bupropion — also reduces cravings.

Ask your clinician — combining a patch with gum, or using varenicline, works better than going it alone.

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Set a Quit Day

  • Pick a date in the next two weeks.
  • Start medication a week before if advised.
  • Clear out cigarettes, vapes, lighters, and ashtrays.
  • Tell a few people so they can cheer you on.

Beat Cravings: the 4 Ds

  • Delay — a craving peaks and passes in a few minutes.
  • Deep breathe — slow breaths reset the urge.
  • Drink water — sip slowly.
  • Distract — move, text someone, keep hands busy.
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Triggers & Slips

Coffee, driving, stress, or a drink can all cue the urge. Plan a new response for each — a different route, a walk, a piece of gum.

A slip is not failure. Learn what triggered it, and get right back on track.

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Get Backup

  • Free coaching: 1-800-QUIT-NOW (1-800-784-8669).
  • Quit apps and text programs help in the moment.
  • Counseling plus medication gives the best results.
The best combination is medication plus support. Neither is "cheating." Using a proven aid and a coach or clinician together roughly doubles your chance of staying quit.