Psychopharmacology

Receptor Binding Profiles — Psychiatric Drug Comparison Tool

Compare receptor binding affinities (Ki values in nM) across psychiatric medication classes. Interactive bar charts and nested treemap visualization showing pKi values for SERT, NET, DAT, 5-HT, dopamine, histamine, alpha, and muscarinic receptors.

Open Interactive Tool

This tool runs in the PsychoPharmRef clinical reference application.

About PsychoPharmRef

PsychoPharmRef is a free clinical psychopharmacology reference built by Jerad Shoemaker, MD for psychiatrists, residents, and medical students. All tools are evidence-based and designed for point-of-care clinical decision support.

  • 91 psychiatric medications with complete pharmacology data
  • 15+ interactive clinical rating scales (PANSS, SLUMS, CDR, PCL-5, Y-BOCS, YMRS, BFCRS, AIMS, and more)
  • Receptor binding profiles with bar chart and treemap visualization
  • PK curve comparison tool with Bateman equation modeling
  • P450 drug interaction checker
  • QTc calculator with Tisdale risk scoring
  • Medication taper and cross-taper planners
  • 68 evidence-based clinical blog posts

PsychoPharmRef Clinical Reference | A resource for medical professionals | Data current as of March 2026

This tool is intended for educational purposes for healthcare professionals. Clinical decision-making should incorporate individual patient assessment and current guidelines.

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